|本期目录/Table of Contents|

[1]刘秋芳,李华.果蝇不同细胞组分转录本多样性[J].生物加工过程,2019,17(02):166-170.[doi:10.3969/j.issn.1672-3678.2019.02.008]
 LIU Qiufang,LI Hua.Transcript diversity of different cellular compartments in Drosophila[J].Chinese Journal of Bioprocess Engineering,2019,17(02):166-170.[doi:10.3969/j.issn.1672-3678.2019.02.008]
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果蝇不同细胞组分转录本多样性()
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《生物加工过程》[ISSN:1672-3678/CN:32-1706/Q]

卷:
17
期数:
2019年02期
页码:
166-170
栏目:
出版日期:
2019-03-30

文章信息/Info

Title:
Transcript diversity of different cellular compartments in Drosophila
文章编号:
1672-3678(2019)02-0166-05
作者:
刘秋芳李华
上海交通大学 生物医学工程学院,上海 200240
Author(s):
LIU QiufangLI Hua
School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China
关键词:
转录本异构体 转录组 翻译组 果蝇
分类号:
Q963;Q756
DOI:
10.3969/j.issn.1672-3678.2019.02.008
文献标志码:
A
摘要:
真核生物基因通过可变转录起始位点、可变剪切和可变多聚腺苷酸化产生多个转录本异构体(transcript isoform)。由于不同转录本异构体的翻译情况有时会有较大的不同,这就导致转录本的多样性和蛋白产物之间的对应关系比较复杂。本文中,笔者收集了果蝇早期胚胎细胞转录组数据和翻译组数据,并通过系统的分析展示了不同细胞组分转录本组成异同。通过对转录组数据和翻译组数据进行比较分析,一共发现766个基因的转录本相对表达水平在果蝇不同细胞组分中发生了改变,这表明在果蝇中大量基因的不同转录本的翻译效率差异可能很大。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2018-02-05修回日期:2018-08-21
基金项目:国家自然科学基金(31501054)
作者简介:刘秋芳(1989—),女,江西上饶人,硕士研究生,研究方向:生物学; 李华(联系人),副研究员,E-mail:kaixinsjtu@gmail.com
引文格式:刘秋芳,李华.果蝇不同细胞组分转录本多样性[J].生物加工过程,2019,17(2):166-170.
LIU Qiufang,LI Hua.Transcript diversity of different cellular compartments in Drosophila[J].Chin J Bioprocess Eng,2019,17(2):166-170..
更新日期/Last Update: 2019-03-30